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System Biology

Description

Introduction to Flux balance analysis, Construction of stoichiometric matrices, Constraint based models. Network basics, examples of mathematical reconstruction of transcriptional networks and signal transduction networks.

What Will I Learn?

  • Tools and databases for modeling: Pathway databases KEGG, EMP, Metacyc, Enzyme kinetics database BRENDA, Gene expression databases, Biomodels database, Basics of Systems Biology Markup Language (SBML), SBML editors.

Topics for this course

5 Lessons50h

SYSTEMS BIOLOGY

Lesson 1-INTRODUCTION
Lesson 2-KINETIC MODELING
Lesson 3-FLUX BALANCE ANALYSIS
Lesson 4-NETWORK MOTIFS AND MODELS
Lesson 5-RESOURCES AND SBML

About the instructor

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518 Courses

2 students

Free

Material Includes

  • Edda Klipp, Wolfram Liebermeister, Christoph Wierling ,Systems Biology a Textbook by Wiley-BlackWell Publications (2009 Edition).
  • Uri Alon , An introduction to Systems Biology: Design Principles of Biological Circuits, (Chapman and Hall / CRC 2007 Edition)
  • Edda Klipp, Ralf Herwig, Axel kowald, Christoph Wierling, Hans Lehrach ,Systems Biology in practice: concepts, implementation and application. (Wiley – VCH 2005)

Requirements

  • B.E/Diploma Students Can Pursue this Course

Target Audience

  • All Engineering Students Can Participate